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April 23, 2026 Dear Reader, We live in the best and the worst of times for vaccines. The benefits of vaccines and vaccination are immense and unmatched by any other medical intervention: immunization prevents millions of deaths every year and reshapes the natural history of multiple infectious diseases.Scientifically, we are in a golden age. Molecular microbiology, structural vaccinology, and “reverse vaccinology” allow us to move from a pathogen genome to plausible vaccine candidates with unprecedented speed, replacing years of empirical trial and error with rational design and versatile platforms. Manufacturing has also globalized: costs have fallen, timelines have shortened, and significant new R&D and production capacity is emerging in low and middle-income countries (LMICs), including mRNA facilities. In principle, we can now design and make high-quality vaccines for most major pathogens, closer to where they are needed. The real constraint is no longer science, but systems. Routine immunization programs are uneven, underfunded, and overstretched; zero-dose or under-immunized populations persist across all regions. In affluent countries, vaccine hesitancy, organized disinformation, and a lack of political will are eroding coverage and slowing the adoption of new vaccines, even as the evidence base grows stronger. This tension is explored in our feature article. This is where ViVa starts each week with our TBE snapshot looking at the Alpine chamois encephalitis virus; the literature news covers topics such as vaccine choices in older adults, measles in LMICs, GBS risks after dengue. You can also stay updated with our vaccine news and the infographic on tick-borne bacterial infections and babesiosis. This week, follow WHO and take the opportunity to check the completeness of your vaccination card! Enjoy the reading! With best wishes for your continued health, and receive the vaccine doses you need. Warm regards, Editor-in-Chief, Global Health Press |
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