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Global Health Press

March 19, 2026

Dear Reader,

Vaccines are often presented as simple: a shot in the arm, a tick in the schedule, a number in an uptake report. Yet the stories in this week’s issue show how incomplete that picture is. Vaccination today sits at the intersection of evolutionary biology, supply chains, and machine learning—and critically political will.

Our diphtheria feature reads like a dispatch from the fault lines of global health: high coverage on paper, immunity gaps in reality, and antitoxin stocks that still behave like rare commodities. Elsewhere in these pages, AI (“immunoinformatics”) turns “from sequence to candidate” into a computational sprint, reminding us that the primary bottlenecks are no longer in design but in validation, manufacturing, and equitable access (Evidence briefs).

We move from the HA head of influenza to higher valent pneumococcal conjugate vaccines, from infants too young for measles vaccination to children at the center of a new mpox clade; and from reassuring data on MVA BN campaigns to the uncomfortable reality that active safety surveillance remains concentrated in high-income countries (VacciNEWS around the globe).

If there is a unifying thesis, it is this: vaccines work astonishingly well—but only as effectively as the systems, data, and governance that surround them.

Enjoy the reading!
With best wishes for your continued health, and receive the vaccine doses you need.

Warm regards,

Signature of Joe Schmitt

Prof. Dr. Joe Schmitt,
Editor-in-Chief, Global Health Press

Highlights of the week
VacciNews Your go-to source for concise updates on the latest developments in the world of vaccines.

This week's VacciNEWS viewpoint:

Health Literacy in Asia

Infographic of the week

VacciTUTOR is our CME-accredited online course dedicated to vaccines and vaccination. Developed by leading international researchers, the course offers over 60 comprehensive chapters covering fundamental topics such as microbiology and immunology, as well as detailed insights into vaccine-preventable diseases and their corresponding vaccines. Concise bullet-point summaries are available free of charge to support quick reference and learning. Feel free to download today’s classical vaccine production infographic. »

VacciNews

The TBE snapshot

Snapshot week 12/2026: Both Siberian (dominant) and Far Eastern subtypes of Tick-borne encephalitis virus are circulating in Kyrgyzstan, with evidence of genetic diversity and cross-border transmission. The presence of the more severe Far Eastern subtype underscores the need for enhanced surveillance and public health focus in this understudied region.


VacciREVIEW

Applied immunoinformatics in modern vaccine design: A review of computational tools

This review highlights how immunoinformatics is transforming vaccine development into a data-driven, precision-based process, integrating immunology, bioinformatics, and AI. By leveraging over 250 computational tools, researchers can rapidly identify antigens, predict immune responses, and optimize vaccine candidates—significantly reducing development time, cost, and improving success rates.

Health Literacy in Asia

Diphtheria on the rise

This week, Health Literacy in Asia highlights the resurgence of diphtheria in regions with low vaccination coverage. Despite being preventable, gaps in routine immunization are driving outbreaks, emphasizing the urgent need for strong vaccination programs and public health vigilance.

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