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March 12, 2026 Dear Reader, The WHO Immunization Agenda 2030 (IA2030) is often described as ambitious, which is a polite way of saying necessary, but inconvenient for budgets and politics. In high-income countries, vaccinology has entered a curious phase where the main constraint is no longer the antigens, but the arms. Measles, pertussis, HPV, adult vaccines in general: the epidemiology increasingly reads like a triumph of science sabotaged by a comment section. We keep inventing ever more sophisticated products, only to leave them stranded in warehouses, guidelines, and carefully worded “shared decision-making” pamphlets.In many low- and middle-income countries, the situation is almost the mirror image. There, willingness to vaccinate is often strong and the disease burden is high, yet health spending per capita would barely cover a streaming subscription. Under such conditions, even the most cost-effective vaccines must compete with syringes, salaries, fuel, and occasionally electricity. To its credit, IA2030 attempts to address both realities at once: vaccines and vaccination — Vi and Va. We chose ViVa as the name for our newsletter because the two belong together. If we achieve Vi without Va, we waste science. If we push Va without thinking about Vi, we discard opportunities that science offers. “ViVa” is therefore not merely a slogan; it is a reminder that success will not be measured in press releases, but in quietly prevented deaths that never trend on social media. This week’s issue reflects that tension between innovation and implementation. TBEV quietly reminds us that flaviviruses can also reach the heart, while our new series on AI in vaccinology explores whether algorithms might one day outpace antivaccine memes. Experiments in mice suggest that nonspecific immune stimulation may protect against a broad gallery of respiratory pathogens. Meanwhile, familiar adversaries such as diphtheria and avian influenza in Vietnam continue to resist retirement. There are also encouraging signs. Early results from the excellent IMPRESS program at the German RKI demonstrate what serious implementation can achieve. New MERS findings from Africa remind us that coronaviruses, like bad ideas, travel well. For that reason, our infographic this week takes aim at persistent vaccine myths.
With all my best wishes, stay healthy—and receive the vaccine doses you need. Warm regards, Editor-in-Chief, Global Health Press |
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